Conjugation of collagen-hybridizing peptides (CHPs) to antibody fragments can improve treatment localization to sites of denatured collagen, potentially limiting on-target effects. Check it out!
In-depth review of the current state of therapeutic anti-cancer antibodies and antibody derivatives. This review acts as a guide, detailing the effects of specific modifications on antibody function, stability, and half-life.
A Tri-part Protein Complementation System Using Antibody-Small Peptide Fusions Enables Homogeneous Immunoassays. Scientific Reports (2017) 7:8186