Conjugation of collagen-hybridizing peptides (CHPs) to antibody fragments can improve treatment localization to sites of denatured collagen, potentially limiting on-target effects. Check it out!
Publication
Publication! WIREs Nanomedicine and Nanobiotechnology – Antibody and antibody derivatives as cancer therapeutics
In-depth review of the current state of therapeutic anti-cancer antibodies and antibody derivatives. This review acts as a guide, detailing the effects of specific modifications on antibody function, stability, and half-life.
https://wires.onlinelibrary.wiley.com/doi/full/10.1002/wnan.1556
First paper on Target-Engaged Complementation published in Scientific Reports
A Tri-part Protein Complementation System Using Antibody-Small Peptide Fusions Enables Homogeneous Immunoassays. Scientific Reports (2017) 7:8186