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Chilling in the Utes stadium

September 20, 2026September 20, 2026Group Member

Christine and Sam’s CoDEPT manuscript published in ACS Medicinal Chemistry Letters

November 6, 2022September 20, 2026owenlab

Complementation Dependent Enzyme Prodrug Therapy Enables Targeted Activation of Prodrug on HER2-Positive Cancer Cells

https://pubs.acs.org/doi/full/10.1021/acsmedchemlett.2c00394

Sun Jin and Morgan’s paper published in Nature Communications

July 15, 2022owenlab
Homogeneous Surrogate Virus Neutralization Assay to Rapidly Assess Neutralization Activity of Anti-SARS-CoV-2 Antibodies https://www.nature.com/articles/s41467-022-31300-9

Vaccinated and finally all back together!

June 4, 2021August 3, 2021owenlab

Keith’s manuscript on Fab-CHP conjugates to treat Rheumatoid Arthritis published in Bioconjugate Chemistry

August 20, 2020August 3, 2021owenlab

Conjugation of collagen-hybridizing peptides (CHPs) to antibody fragments can improve treatment localization to sites of denatured collagen, potentially limiting on-target effects. Check it out!

https://pubs.acs.org/doi/10.1021/acs.bioconjchem.0c00324

Publication

Keith is awarded the University Graduate Research Fellowship

May 22, 2019August 3, 2021owenlab

Congratulations to Keith Arlotta for receiving funding through the University of Utah Graduate School!

Funding

Publication! WIREs Nanomedicine and Nanobiotechnology – Antibody and antibody derivatives as cancer therapeutics

May 22, 2019August 3, 2021owenlab

In-depth review of the current state of therapeutic anti-cancer antibodies and antibody derivatives. This review acts as a guide, detailing the effects of specific modifications on antibody function, stability, and half-life.

https://wires.onlinelibrary.wiley.com/doi/full/10.1002/wnan.1556

Publication

Sam receives support through UROP

December 14, 2017August 3, 2021owenlab

Congrats to Sam Hatch for receiving funding through the University of Utah Undergraduate Research Opportunity Program.

Funding

First paper on Target-Engaged Complementation published in Scientific Reports

August 15, 2017August 3, 2021owenlab
https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41598-017-07569-y/MediaObjects/41598_2017_7569_Fig1_HTML.jpg

A Tri-part Protein Complementation System Using Antibody-Small Peptide Fusions Enables Homogeneous Immunoassays. Scientific Reports (2017) 7:8186

https://www.nature.com/articles/s41598-017-07569-y

Publication

Scholarship! Sun Jin received a Skaggs Research Fellowship

August 15, 2017August 3, 2021owenlab

Congratulations to Sun Jin Kim (bottom right) as one of four graduate students to receive a Skaggs Research Fellowship.

 Much thanks to the College of Pharmacy and the ALSAM Foundation.

Funding

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Current Thoughts:

“The most exciting phrase to hear in science, the one that heralds the most discoveries, is not ‘Eureka!’ but ‘That’s funny…'” — Isaac Asimov

“If your experiment needs statistics, you ought to have done a better experiment.” — Ernest Rutherford”

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