Publications

GOOGLE SCHOLAR LINK

25. Split‐enzyme fragment as a single affinity tag that enables protein expression, purification, and functional assays. SJ Kim, ST Hatch, AS Dixon, SC Owen, Biotechnology and Bioengineering, 2019, In Press

24. Antibody and Antibody-Derivatives as Cancer Therapeutics. KJ Arlotta, SC Owen, WIREs Nanomedicine and Nanobiotechnology, 2019, Apr; https://doi.org/10.1002/wnan.1556

23. Biophysical Properties and Heating-Induced Aggregation of Lysine-Conjugated Antibody-Drug Conjugates AV Gandhi, KJ Arlotta, HN Chen, SC Owen, JF Carpenter, J Pharm Sci., 2018, Jul;107(7):1858-1869. doi:10.1016/j.xphs.2018.03.022

22. In-Depth Comparison of Lysine-Based Antibody-Drug Conjugates Prepared on Solid Support Versus in Solution. KJ Arlotta, AV Gandhi, HN Chen, CS Nervig, JF Carpenter, SC Owen, Antibodies, 2018 7 (1), 6

21. A Tri-part Protein Complementation System Using Antibody-Small Peptide Fusions Enables Homogeneous Immunoassays. Dixon AS, Kim SJ, Baumgartner BK, Krippner S, Owen SC, Sci Rep, 2017, 7(1), 8186

20. Imiquimod Induces Apoptosis in Human Endometrial Cancer Cells In vitro and Prevents Tumor Progression In vivo. Almomen A, Jarboe EA, Dodson MK, Peterson CM, Owen SC, Janat-Amsbury MM,  Pharm Res, 2016, 33, 2209

19. Tuning the Microenvironment: Click-Crosslinked Hyaluronic Acid-Based Hydrogels Provide a Platform for Studying Breast Cancer Cell Invasion. Fisher SA, Anandakumaran PN, Owen SC, Shoichet MS, Adv Funct Mater, 2015, 25(46), 7163-7172

18. JR McCombs, SC Owen. Antibody Drug Conjugates: Design and Selection of Linker, Payload and Conjugation Chemistry; The AAPS Journal, 2015, 17 (2), 339-351 doi: 10.1208/s12248-014-9710-8

17. J Logie, SC Owen, CK McLaughlin, MS Shoichet. PEG-Graft Density Controls Polymeric Nanoparticle Micelle Stability, Chemistry of Materials, 2014, 26 (9), 2847-2855 doi: 10.1021/cm500448x

16. RY Tam, SC Owen, MS Shoichet. ECM-Inspired Chemical Cues: Biomimetic Molecules and Techniques of Immobilization, Bio-Inspired Materials for Biomedical Engineering, John Wiley & Sons, New Jersey, 2014, 7-24 doi: 10.1002/9781118843499.ch1

15. SC Owen, AK Doak, AN Ganesh, L Nedyalkova, CK McLaughlin, BK Shoichet, MS Shoichet. Colloidal Drug Formulations Can Explain “Bell-Shaped” Concentration-Response Curves, ACS Chemical Biology, 2014, 9 (3), 777-784 doi: 10.1021/cb4007584

14. SC Owen, N Patel, JG Pan, H Persson, SS Sidhu, MS Shoichet. Targeting HER2+ breast cancer cells: Lysosomal accumulation of anti-HER2 antibodies is influenced by antibody binding site and conjugation to polymeric nanoparticles, Journal of Controlled Release, 2013, 172 (2), 395-404 doi: 10.1016/j.jconrel.2013.07.011

13. DPY Chan, GF Deleavey, SC Owen, MJ Damha, MS Shoichet. Delivery of siRNA and Antisense Oligoculeotides using Dual Functional Polymeric Immuno-nanoparticles, Biomaterials, 2013, 34 (33), 8408-8415 doi: 10.1016/j.biomaterials.2013.07.019

12. SC Owen, RY Tam, SM Fisher, MS Shoichet. User-controlled Architecture and Physical Properties of Diels-Alder Click Hydrogels, Langmuir 2013, 29 (24), 7393-7400 doi: 10.1021/la305000w

11. DPY Chan*, SC Owen*, MS Shoichet. Double Click: Dual Functionalized Polymeric Micelles Bioconjugate Chemistry, 2013, 24 (2), 105-113 doi: 10.1021/bc300511a *equal contribution

10. KS Ho, PC Poon, SC Owen, MS Shoichet. Blood Vessel Hyperpermeability and pathophysiology in Human Tumour Xenograft Models of Breast Cancer: A Comparison of Ectopic and Orthotopic Tumours, BMC Cancer, 2012, 12 (1), 579 doi: 10.1186/1471-2407-12-579

9. SC Owen*, AK Doak*, P Wassam, MS Shoichet, BK Shoichet. Colloidal Aggregation Affects the Efficacy of Anticancer Drugs in Cell Culture, ACS Chemical Biology, 2012, 7 (8), 1429-1435
doi: 10.1021/cb300189b *equal contribution

8. CM Terry, L Li, H Li, I Zhuplatov, DK Blumenthal, SE Kim, SC Owen, EG Kholmovski, KD Fowers, R Rathi, AK Cheung. In Vivo Evaluation of the Delivery and Efficacy of a Sirolimus-Laden Polymer Gel for Inhibition of Hyperplasia in a Porcine Model of Arteriovenous Hemodialysis Graft Stenosis, Journal of Controlled Release, 2012, 160 (3), 459-467 doi: 10.1016/j.jconrel.2012.03.011

7. SC Owen, DPY Chan, MS Shoichet. Polymeric Micelle Stability, Nanotoday, 2012, 7, 53-65
doi: 10.1016/j.nantod.2012.01.002

6. Y Aizawa*, SC Owen*, MS Shoichet. Polymers Used to Influence Cell Fate, Progress in Polymer Science, 2012, 37 (5), 645-658 doi: 10.1016/j.progpolymsci.2011.11.004 *equal contribution

5. J Lu, SC Owen, MS Shoichet. Stability of Self-Assembled Polymeric Micelles in Serum, Macromolecules, 2011, 44, 6002-6008 doi: 10.1021/ma200675w

4. CM Nimmo, SC Owen, MS Shoichet. Diels-Alder Click Cross-Linked Hyaluronic Acid Hydrogels for Tissue Engineering, Biomacromolecules, 2011, 12, 824-830 doi: 10.1021/bm101446k

3. SC Owen, MS Shoichet. Design of Three-Dimensional Biomimetic Scaffolds, Journal of Biomedical Materials Research Part A, 2010, 94A, 1321-1331 doi: 10.1002/jbm.a.32834

2. SC Owen, H Li, AK Cheung, CM Terry. Correlation of Tissue Drug Concentrations With In Vivo Magnetic Resonance Images of Polymer Drug Depot Around Arteriovenous Graft, Journal of Controlled Release, 2010, 146, 23-30 doi:10.10.1016/jconrel.2010.05.005

1. SC Owen, M Lee, CB Grissom. Characterization of Natural Cobalamin Analogs by Ultra Performance Liquid Chromatography Tandem Quadropole Mass Spectrometry, Journal of Chromatographic Science, 2011, 49 (3), 228-233 IDS Number: 724CA